MLD Information
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Metachromatic leukodystrophy (MLD) is one of a group of genetic disorders called
the leukodystrophies. These diseases impair the growth or development of the
myelin sheath, the fatty covering that acts as an insulator around nerve fibers.
Myelin, which lends its color to the white matter of the brain, is a complex
substance made up of at least 10 different enzymes. The leukodystrophies are
caused by genetic defects in how myelin produces or metabolizes these enzymes.
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| | - National Institute Of Neurological Disorders
and Stroke |
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